Fertility Challenges Find out more about fertility challenges Miscarriage Along the pregnancy journey, miscarriage can happen. It is a difficult and emotional time of for loss couples. One in five confirmed pregnancies will end in miscarriage. Endometriosis Endometriosis normally presents in women between 20-40 years of age and can be very painful. Polycystic Ovarian Syndrome (PCOS) PCOS is common, occurring in about 10% of all women of reproductive age and a common cause of infertility. Fibroids Fibroids are common. Anyone with a uterus can get fibroids. As a female, you many have many over the course of your lifetime. Blocked Fallopian Tubes Blocked fallopian tubes is a common cause of infertility and is diagnosed in 25-35% of infertile women.